Fibrinogen and catheter advancement difficulty: unveiling the key predictors of early in-situ bleeding after peripherally inserted central catheter insertion - Takeaways - MDSpire

Fibrinogen and catheter advancement difficulty: unveiling the key predictors of early in-situ bleeding after peripherally inserted central catheter insertion

  • By

  • Shusheng Jiao

  • Hongjie Yang

  • Jianling Yang

  • Jianxia Zhi

  • July 15, 2026

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  • 1

    The study analyzed factors associated with early puncture site bleeding following PICC placement in a cohort of 375 patients.

  • 2

    The incidence of in-situ hemorrhage within 48 hours post-PICC insertion was found to be 21.9% among the study participants.

  • 3

    Lower fibrinogen levels and difficulty in catheter advancement were identified as independent risk factors for early bleeding.

  • 4

    An unexpected association indicated that a tumor diagnosis may reduce the risk of bleeding, warranting further investigation.

  • 5

    The findings emphasize the importance of pre-procedural coagulation assessment and careful catheter placement techniques.

Original Source(s)

Fibrinogen and catheter advancement difficulty: unveiling the key predictors of early in-situ bleeding after peripherally inserted central catheter insertion

  • by Shusheng Jiao, Hongjie Yang, Jianling Yang, Jianxia Zhi

  • July 15, 2026

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