Effects of Setup Errors on Dose Distribution in Hypofractionated Radiotherapy for Left-Sided Radical Breast Cancer - Takeaways - MDSpire

Effects of Setup Errors on Dose Distribution in Hypofractionated Radiotherapy for Left-Sided Radical Breast Cancer

  • By

  • Pan Wang

  • Guofeng Ma

  • Ting Zhao

  • Wei Ding

  • Wei Kong

  • Hongqiang Ye

  • Jun Shang

  • Wanfu Yang

  • April 24, 2026

  • 0 min

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  • 1

    Setup errors significantly impact dose distribution in hypofractionated radiotherapy for left-sided radical breast cancer.

  • 2

    CTVsc and CTVcw are most sensitive to setup errors in the superior and anterior directions, respectively.

  • 3

    Increased positioning errors from 3 mm to 9 mm lead to substantial decreases in D95% for both CTVsc and CTVcw.

  • 4

    The esophagus and thyroid are particularly sensitive to setup errors in the right direction, while the heart and LAD are sensitive in the posterior direction.

  • 5

    A setup error tolerance of 3 mm is recommended for CTVcw and OARs, while a tolerance of 5 mm may be acceptable for CTVsc.

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