The influence of C-reactive protein-triglyceride-glucose index (CTI) on the prognosis of heart failure patients with different ejection fractions - Takeaways - MDSpire

The influence of C-reactive protein-triglyceride-glucose index (CTI) on the prognosis of heart failure patients with different ejection fractions

  • By

  • Xinuo Ma

  • Feng Wang

  • Dajin Liu

  • Ying Li

  • Ping Xia

  • Yunyun Xu

  • Han Xia

  • Yujuan Peng

  • Lixing Chen

  • June 8, 2026

  • 0 min

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  • 1

    The C-reactive protein-triglyceride-glucose index (CTI) is a novel biomarker that integrates inflammation and insulin resistance.

  • 2

    Elevated CTI levels are associated with a significantly higher risk of all-cause mortality in patients with chronic heart failure.

  • 3

    CTI serves as an independent prognostic marker for all-cause mortality across different ejection fraction subtypes in heart failure patients.

  • 4

    Subgroup analysis indicates that higher CTI levels correlate with increased mortality in patients with heart failure with reduced and mildly reduced ejection fraction.

  • 5

    The study emphasizes the importance of CTI as a potential tool for risk stratification in chronic heart failure management.

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