Glandular tissue–based versus anatomical landmark–based CTV delineation in postoperative breast cancer radiotherapy: a dosimetric comparison

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Glandular tissue-based CTV delineation resulted in significantly smaller volumes compared to anatomical landmark-based delineation.
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Patients using glandular-based delineation experienced lower maximum doses and reduced exposure to organs at risk, including the heart and lungs.
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The study included 48 breast cancer patients, with a mean age of 49.35 years, all undergoing postoperative radiotherapy.
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Significant dosimetric advantages were observed for the glandular approach, with lower heart and contralateral breast doses.
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Further research is needed to assess the clinical implications of these dosimetric findings on long-term toxicity and treatment decisions.

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