Treatment of congenital toxoplasmosis with pyrimethamine combined with sulfadiazine in a Chinese neonate: a case report - Takeaways - MDSpire

Treatment of congenital toxoplasmosis with pyrimethamine combined with sulfadiazine in a Chinese neonate: a case report

  • By

  • Ya Hu

  • Jingsong Wang

  • Zhenlong Wang

  • Yu Zhang

  • XiaoYa He

  • Min Zhao

  • Sirao Lu

  • Bo Zhang

  • Ya Yang

  • June 26, 2026

  • 0 min

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  • 1

    A male infant diagnosed with congenital toxoplasmosis was treated with pyrimethamine and sulfadiazine after initial empirical therapy with azithromycin.

  • 2

    The infant was born at 36⁺⁶ weeks of gestation and presented with jaundice but showed no severe symptoms during the course of illness.

  • 3

    Due to limited drug accessibility in China, the standard treatment regimen was initiated only after family-sourced medications were obtained.

  • 4

    The infant tolerated the treatment well, with no significant adverse reactions reported during the one-year follow-up.

  • 5

    This case illustrates the feasibility of implementing standard congenital toxoplasmosis treatment in China despite drug accessibility challenges.

Original Source(s)

Treatment of congenital toxoplasmosis with pyrimethamine combined with sulfadiazine in a Chinese neonate: a case report

  • by Ya Hu, Jingsong Wang, Zhenlong Wang, Yu Zhang, XiaoYa He, Min Zhao, Sirao Lu, Bo Zhang, Ya Yang

  • June 26, 2026

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