Symptom Scores May Signal Neuropathy Risk - Takeaways - MDSpire

Symptom Scores May Signal Neuropathy Risk

  • By

  • Andrea Surnit

  • May 6, 2026

  • 4 min

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  • 1

    Patient-reported symptom scores can identify oropharyngeal cancer survivors at higher risk for delayed hypoglossal nerve neuropathy.

  • 2

    The study analyzed 1,297 patients treated at MD Anderson Cancer Center from 2015 to 2023 using the MDASI-HN-NERVE score.

  • 3

    Each 1-point increase in the MDASI-HN-NERVE score was associated with a 1.35-fold higher hazard of developing neuropathy.

  • 4

    Patients with baseline scores of at least 3.4 had lower neuropathy-free survival through 60 months compared to those with lower scores.

  • 5

    The findings support symptom-based surveillance as a potential tool for risk stratification in oropharyngeal cancer survivors.

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