Symptom Scores May Signal Neuropathy Risk
Early recovery symptom patterns may help clinicians identify which oropharyngeal cancer survivors warrant closer neurologic surveillance.
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By
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Andrea Surnit
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May 6, 2026
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Patient-reported symptom scores can identify oropharyngeal cancer survivors at higher risk for delayed hypoglossal nerve neuropathy.
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The study analyzed 1,297 patients treated at MD Anderson Cancer Center from 2015 to 2023 using the MDASI-HN-NERVE score.
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Each 1-point increase in the MDASI-HN-NERVE score was associated with a 1.35-fold higher hazard of developing neuropathy.
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Patients with baseline scores of at least 3.4 had lower neuropathy-free survival through 60 months compared to those with lower scores.
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The findings support symptom-based surveillance as a potential tool for risk stratification in oropharyngeal cancer survivors.