Enhancing procedural quality and efficiency of methacholine bronchial challenge tests in patients with suspected cough-variant asthma: a quasi-experimental study utilizing nurse–patient communication and respiratory training - Takeaways - MDSpire

Enhancing procedural quality and efficiency of methacholine bronchial challenge tests in patients with suspected cough-variant asthma: a quasi-experimental study utilizing nurse–patient communication and respiratory training

  • By

  • Yu Hu

  • Hailun Wang

  • Chang Tan

  • Yu He

  • Jin Zhu

  • Shi Chen

  • Tian Zhao

  • Enhong Liu

  • Ying Chen

  • Sisi Chen

  • Beibei Zhang

  • Hongmei Xiang

  • Fajiu Li

  • Xuecun Wang

  • July 1, 2026

  • 0 min

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  • 1

    The study evaluated the impact of COMFORT-based nurse-patient communication and respiratory training on methacholine bronchial challenge tests.

  • 2

    The intervention group had a significantly higher first-attempt success rate compared to the control group (75.6% vs. 24.4%, p < 0.001).

  • 3

    In-chamber testing duration was shorter for the intervention group, averaging 11.85 minutes compared to 16.90 minutes for controls (p < 0.001).

  • 4

    Post-procedure anxiety and distress scores were lower in the intervention group, indicating reduced psychological burden during testing.

  • 5

    Mild procedure-related adverse events were less frequent in the intervention group (7.3% vs. 24.4%, p = 0.032), suggesting improved safety.

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