AI-driven analysis of retinal images may support earlier risk stratification for dementia and stroke, but evidence for improved clinical outcomes is insufficient.
2
Nearly half of dementia cases may be preventable or delayed through risk factor modification, and up to 80% of strokes can be prevented with timely detection.
3
The retina's shared characteristics with the central nervous system make it a potential site for assessing brain health through AI-driven 'oculomics'.
4
Most oculomics models are in early clinical evaluation and have been judged by technical performance metrics, which may not establish clinical usefulness.
5
The authors call for clearer definitions and regulatory standards for oculomics tools, emphasizing they should complement existing screening strategies.
