Bone mineral density and bone turnover in adolescent girls with anorexia nervosa: a 3-year retrospective cohort study - Takeaways - MDSpire

Bone mineral density and bone turnover in adolescent girls with anorexia nervosa: a 3-year retrospective cohort study

  • By

  • Dorota Roztoczyńska

  • Aleksandra Roztoczyńska

  • Jerzy Starzyk

  • May 11, 2026

  • 0 min

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  • 1

    Adolescent girls with anorexia nervosa are at high risk for reduced bone mineral density due to chronic malnutrition and endocrine disturbances.

  • 2

    The study followed 36 adolescent girls with anorexia nervosa over three years, assessing bone density, turnover markers, and hormonal parameters.

  • 3

    The most significant bone mineral density loss occurred within the first 12-24 months, with partial recovery noted by 36 months.

  • 4

    Hormonal therapy, along with calcium and vitamin D supplementation, positively influenced bone mineral density recovery.

  • 5

    Bone recovery in these patients is linked to both weight restoration and normalization of endocrine function, with skeletal improvement lagging.

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