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1
Adolescent girls with anorexia nervosa are at high risk for reduced bone mineral density due to chronic malnutrition and endocrine disturbances.
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2
The study followed 36 adolescent girls with anorexia nervosa over three years, assessing bone density, turnover markers, and hormonal parameters.
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3
The most significant bone mineral density loss occurred within the first 12-24 months, with partial recovery noted by 36 months.
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4
Hormonal therapy, along with calcium and vitamin D supplementation, positively influenced bone mineral density recovery.
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5
Bone recovery in these patients is linked to both weight restoration and normalization of endocrine function, with skeletal improvement lagging.