Klebsiella pneumoniae septic pulmonary embolism from renal vein thrombosis - Takeaways - MDSpire
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Septic Pulmonary Embolism Due to Klebsiella pneumoniae Arising from Renal Vein Thrombosis

  • By

  • Makoto Nojo

  • Shin Ohta

  • Yosuke Fukuda

  • Tomohiro Matsunaga

  • Yoshitaka Uchida

  • Nao Sato

  • Sae Kawafune

  • Ryo Manabe

  • Yasunari Kishino

  • Hironori Sagara

  • Akihiko Tanaka

  • August 22, 2026

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  • 1

    A 47-year-old woman with untreated diabetes presented with dysuria, 11 days of fever, abdominal pain, and hypoxemia; blood and urine cultures grew Klebsiella pneumoniae.

  • 2

    CT showed left pyelonephritis, renal abscesses, a near-occlusive thrombus extending from the left renal vein into the inferior vena cava, pulmonary arterial emboli, and bilateral peripheral cavitary nodules.

  • 3

    Bacteremia persisted despite meropenem; the isolate was susceptible to ceftriaxone and levofloxacin and had a positive string test supporting a hypermucoviscous phenotype.

  • 4

    Continued antimicrobial therapy, anticoagulation, and insulin treatment were followed by clinical, laboratory, and radiographic improvement by day 38 without surgical intervention.

  • 5

    More than 4 years after antimicrobial therapy ended, no infection, thrombosis, or septic pulmonary embolism had recurred.

Original Source(s)

Klebsiella pneumoniae septic pulmonary embolism from renal vein thrombosis

  • by Makoto Nojo, Shin Ohta, Yosuke Fukuda, Tomohiro Matsunaga, Yoshitaka Uchida, Nao Sato, Sae Kawafune, Ryo Manabe, Yasunari Kishino, Hironori Sagara, Akihiko Tanaka

  • August 22, 2026

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