Timing Considerations for Endovascular Intervention in Patients with Symptomatic Intracranial Atherosclerotic Stenosis: Insights from a Single-Center Real-World Analysis - Takeaways - MDSpire

Timing Considerations for Endovascular Intervention in Patients with Symptomatic Intracranial Atherosclerotic Stenosis: Insights from a Single-Center Real-World Analysis

  • By

  • Yang Yang

  • Xiaoya Wang

  • Jialiang Lu

  • Ye Li

  • Lili Zhao

  • Yating Jian

  • Tao Li

  • Meijuan Dang

  • Ziwei Lu

  • Fangcun Li

  • Fan Tang

  • Qingyu Fan

  • Ning Bu

  • Huqing Wang

  • Ru Zhang

  • An Wen

  • Guilian Zhang

  • Hong Fan

  • Lei Zhang

  • April 22, 2026

  • 0 min

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  • 1

    The study analyzed 174 patients with symptomatic intracranial atherosclerotic stenosis undergoing endovascular intervention.

  • 2

    Early intervention (≤14 days) showed 30-day stroke or death rates of 11.3%, while delayed intervention (>14 days) had rates of 8.3%.

  • 3

    Factors influencing intervention timing included preoperative NIHSS, albumin-to-globulin ratio, and LDL levels.

  • 4

    For anterior circulation sICAS with minor strokes, intervention timing may be flexible, while basilar artery lesions favor delayed intervention.

  • 5

    The findings suggest the need for further prospective studies to validate the optimal timing for endovascular treatment in sICAS patients.

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