Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction - Takeaways - MDSpire

Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction

  • By

  • Gong Yuqianhui

  • Liu Yuanya

  • Zhang Hao

  • Wen Zhanpeng

  • Quan Yong

  • Feng Li

  • Huang Xuansheng

  • Sun Yanxiang

  • July 3, 2026

  • 0 min

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  • 1

    The study included 170 hospitalized patients with sleep apnea, divided into HFpEF (n=96) and non-HFpEF (n=74) groups.

  • 2

    Patients with HFpEF exhibited significantly higher left atrial diameter, apnea-hypopnea index, epicardial adipose tissue volume, and NT-proBNP levels.

  • 3

    Multivariate logistic regression identified female sex, NT-proBNP level, left atrial diameter, and epicardial adipose tissue volume as independent predictors of HFpEF.

  • 4

    A combined model of these predictors achieved an area under the curve of 0.971 for discriminating HFpEF in sleep apnea patients.

  • 5

    Cox regression analysis indicated that NT-proBNP was independently associated with poor prognosis among sleep apnea patients with HFpEF.

Original Source(s)

Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction

  • by Gong Yuqianhui, Liu Yuanya, Zhang Hao, Wen Zhanpeng, Quan Yong, Feng Li, Huang Xuansheng, Sun Yanxiang

  • July 3, 2026

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