Intralesional Vitamin D versus Triamcinolone Acetonide for the Treatment of Keloids: A Systematic Review and Meta-analysis of Randomized Controlled Trials - Takeaways - MDSpire

Intralesional Vitamin D versus Triamcinolone Acetonide for the Treatment of Keloids: A Systematic Review and Meta-analysis of Randomized Controlled Trials

  • By

  • Jiang, Dan

  • Liu, Yalan

  • Li, Sheng

  • Wang, Ximao

  • You, Shunjie

  • May 22, 2026

  • 0 min

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  • 1

    Intralesional triamcinolone acetonide (TAC) is the standard nonsurgical treatment for keloids but has steroid-related adverse effects.

  • 2

    This meta-analysis compared the efficacy and safety of intralesional vitamin D and TAC in managing keloids.

  • 3

    TAC showed superior efficacy in improving scar severity and lesion flattening compared to vitamin D.

  • 4

    Vitamin D was linked to lower risks of pigmentation changes and skin atrophy compared to TAC.

  • 5

    The findings suggest vitamin D may be suitable for patients concerned about steroid-related side effects.

Original Source(s)

Intralesional Vitamin D versus Triamcinolone Acetonide for the Treatment of Keloids: A Systematic Review and Meta-analysis of Randomized Controlled Trials

  • by Jiang, Dan , Liu, Yalan , Li, Sheng , Wang, Ximao , You, Shunjie

  • May 22, 2026

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