Postoperative speech impairment and cranial nerve deficits in children undergoing posterior fossa tumor surgery with intraoperative MRI – a prospective multinational study - Takeaways - MDSpire

Postoperative speech impairment and cranial nerve deficits in children undergoing posterior fossa tumor surgery with intraoperative MRI – a prospective multinational study

  • By

  • Aske Foldbjerg Laustsen

  • Jonathan Kjær Grønbæk

  • Radek Frič

  • Shivaram Avula

  • Conor Mallucci

  • Pelle Nilsson

  • Per Nyman

  • Péter Hauser

  • Katalin Mudra

  • Rosita Kiudeliene

  • Saulius Ročka

  • Magnus Aasved Hjort

  • Rick Brandsma

  • Eelco Hoving

  • Andrea Carai

  • Vladimír Beneš

  • Jana Táborská

  • Christian Dorfer

  • Sandra Jacobs

  • Miriam Pavon-Mengual

  • Jane Skjøth-Rasmussen

  • Kjeld Schmiegelow

  • Astrid Sehested

  • René Mathiasen

  • Marianne Juhler

  • September 22, 2025

  • 0 min

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  • 1

    Gross total resection of pediatric posterior fossa tumors risks complications like cerebellar mutism syndrome and cranial nerve deficits.

  • 2

    Postoperative speech impairment, a key component of cerebellar mutism syndrome, can severely affect children after posterior fossa tumor surgery.

  • 3

    Intraoperative MRI has been increasingly used in pediatric neurosurgery, improving tumor localization and resection outcomes.

  • 4

    This study is the first large-scale multinational assessment of risks for postoperative speech impairment and cranial nerve damage with ioMRI.

  • 5

    The observational study included children under 18 undergoing surgery for posterior fossa tumors, assessing neurological and speech outcomes postoperatively.

Original Source(s)

Postoperative speech impairment and cranial nerve deficits in children undergoing posterior fossa tumor surgery with intraoperative MRI – a prospective multinational study

  • by Aske Foldbjerg Laustsen, Jonathan Kjær Grønbæk, Radek Frič, Shivaram Avula, Conor Mallucci, Pelle Nilsson, Per Nyman, Péter Hauser, Katalin Mudra, Rosita Kiudeliene, Saulius Ročka, Magnus Aasved Hjort, Rick Brandsma, Eelco Hoving, Andrea Carai, Vladimír Beneš, Jana Táborská, Christian Dorfer, Sandra Jacobs, Miriam Pavon-Mengual, Jane Skjøth-Rasmussen, Kjeld Schmiegelow, Astrid Sehested, René Mathiasen, Marianne Juhler

  • September 22, 2025

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