The effects of high-intensity interval training on glucose metabolism, inflammatory responses, and functional recovery in patients with diabetic peripheral neuropathy - Takeaways - MDSpire

The effects of high-intensity interval training on glucose metabolism, inflammatory responses, and functional recovery in patients with diabetic peripheral neuropathy

  • By

  • Genchun Guo

  • Zhenhua Zhu

  • Xin Shao

  • Feixiang Ma

  • Chunyan Xing

  • Yunlan Huang

  • Wanlang Li

  • June 18, 2026

  • 0 min

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  • 1

    High-intensity interval training (HIIT) significantly improves glucose metabolism and reduces inflammation in patients with diabetic peripheral neuropathy (DPN).

  • 2

    A total of 93 patients with DPN participated in a 12-week randomized controlled trial comparing HIIT, moderate-intensity continuous training (MICT), and a control group.

  • 3

    Both HIIT and MICT improved fasting plasma glucose, glycated hemoglobin, and nerve conduction velocities compared to the control group.

  • 4

    HIIT showed more significant and sustained improvements in clinical outcomes, including HbA1c and inflammatory markers, compared to MICT.

  • 5

    The study provides evidence that HIIT is superior to MICT for exercise rehabilitation in patients with DPN, enhancing both metabolic and neurological recovery.

Original Source(s)

The effects of high-intensity interval training on glucose metabolism, inflammatory responses, and functional recovery in patients with diabetic peripheral neuropathy

  • by Genchun Guo, Zhenhua Zhu, Xin Shao, Feixiang Ma, Chunyan Xing, Yunlan Huang, Wanlang Li

  • June 18, 2026

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