Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster - Takeaways - MDSpire

Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster

  • By

  • Folasade P. May

  • Suzanne Brodney

  • Jessica J. Tuan

  • Sapna Syngal

  • Andrew T. Chan

  • Beth Glenn

  • Gina Johnson

  • Yuchiao Chang

  • David A. Drew

  • Beverly Moy

  • Nicolette J. Rodriguez

  • Erica T. Warner

  • Adjoa Anyane-Yeboa

  • Chinedu Ukaegbu

  • Anjelica Q. Davis

  • Kimberly Schoolcraft

  • Susan Regan

  • Kelley Le Beaux

  • Ellen T. Lee

  • Roopa Bhat

  • Alexis Gordon

  • Linh K. Phan

  • Andrea Fernanda Cortés Chirino

  • Caylin J. Marotta

  • Rachel G. Z. Kindermann

  • Jennifer S. Haas

  • June 1, 2026

  • 0 min

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  • 1

    Colorectal cancer is the second leading cause of cancer mortality in the US, particularly affecting underresourced populations.

  • 2

    Community health centers have lower colorectal cancer screening rates due to various patient, clinician, and health system factors.

  • 3

    Mailed outreach significantly increased colorectal cancer screening participation, with 30% of patients completing screening compared to 9.7% without outreach.

  • 4

    The CARES study compares mailed FIT outreach and FIT-DNA with patient assistance to enhance screening uptake in community health clinics.

  • 5

    Participants received mailed kits and reminders in English or Spanish, with follow-up navigation offered for those with abnormal screening results.

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