The cortisol stress response following surgery for proximal femur fractures in geriatric patients – a prospective pilot study - Takeaways - MDSpire

The cortisol stress response following surgery for proximal femur fractures in geriatric patients – a prospective pilot study

  • By

  • Menger, Maximilian M.

  • Streck, Laura E.

  • Braun, Benedikt J.

  • Herath, Steven C.

  • Audretsch, Christof K.

  • Bamberg, Maximilian

  • Menger, Michael D.

  • Histing, Tina

  • Fontana, Johann

  • March 30, 2026

  • 0 min

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  • 1

    Aging affects the suprachiasmatic nucleus, impairing cortisol stress response and potentially increasing postoperative complications.

  • 2

    The study focused on 20 geriatric patients with proximal femur fractures, assessing their cortisol levels post-surgery.

  • 3

    35% of patients had cortisol levels below the critical threshold of 276 nmol/L, indicating potential corticosteroid insufficiency.

  • 4

    A significant correlation was found between IL-6 levels and cortisol, while other markers showed no predictive value.

  • 5

    Postoperative cortisol monitoring is recommended for geriatric patients to identify those needing treatment to improve outcomes.

Original Source(s)

The cortisol stress response following surgery for proximal femur fractures in geriatric patients – a prospective pilot study

  • by Menger, Maximilian M., Streck, Laura E., Braun, Benedikt J., Herath, Steven C., Audretsch, Christof K., Bamberg, Maximilian , Menger, Michael D., Histing, Tina , Fontana, Johann

  • March 30, 2026

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