High prevalence of viral hepatitis in a series of splenic marginal zone lymphomas from Romania - Takeaways - MDSpire

High prevalence of viral hepatitis in a series of splenic marginal zone lymphomas from Romania

  • By

  • B Fetica

  • B Pop

  • M L Blaga

  • A Fulop

  • D Dima

  • M T Zdrenghea

  • C I Vlad

  • A S Bojan

  • P Achimas-Cadariu

  • C I Lisencu

  • A Irimie

  • D D Weisenburger

  • November 11, 2016

  • 0 min

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  • 1

    Splenic marginal zone lymphoma (SMZL) accounted for 4.65% of all lymphoma cases in a Romanian study of 731 patients from 2006 to 2016.

  • 2

    The study identified a high prevalence of viral hepatitis, with 29% of patients diagnosed with hepatitis B or C among those tested for viral infections.

  • 3

    The male-to-female ratio in SMZL cases was 1.8, with a median patient age of 63 years, showing no significant age difference between genders.

  • 4

    Immunohistochemical analysis revealed that SMZL cells were positive for pan-B-cell markers and negative for several other markers, indicating specific lymphoma characteristics.

  • 5

    Survival analysis suggested a borderline difference in overall survival between patients with and without viral hepatitis, highlighting potential prognostic implications.

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