Creation and assessment of a nomogram for predicting the invasiveness of stage T1 lung adenocarcinoma preoperatively using AI-based radiomic analysis - Takeaways - MDSpire

Creation and assessment of a nomogram for predicting the invasiveness of stage T1 lung adenocarcinoma preoperatively using AI-based radiomic analysis

  • By

  • Wensong Shi

  • Yuzhui Hu

  • Guotao Chang

  • Yulun Yang

  • He Qian

  • Yinsen Song

  • Zhengpan Wei

  • Liang Gao

  • Hang Yi

  • Sikai Wu

  • Kun Wang

  • Huandong Huo

  • Yousheng Mao

  • Yingli Sun

  • Ming Li

  • Siyuan Ai

  • Liang Zhao

  • Xiangnan Li

  • Huiyu Zheng

  • January 7, 2026

  • 0 min

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  • 1

    The study develops a nomogram using AI-based radiomic analysis to predict the invasiveness of T1 lung adenocarcinoma preoperatively.

  • 2

    It utilizes data from six medical centers, analyzing 1523 nodules with confirmed postoperative pathology and thin-section chest CT imaging.

  • 3

    The classification distinguishes between non-invasive groups (AAH, AIS, MIA) and the invasive group (IAC) to aid in clinical decision-making.

  • 4

    AI-enhanced radiomic analysis addresses variability in manual imaging assessments, improving objectivity and reproducibility in lung cancer diagnosis.

  • 5

    The findings aim to support preoperative planning and enhance the differentiation of T1-stage invasive lung cancer for better surgical outcomes.

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