Distinct Gut Microbiota Signatures Associated With Progression of Atherosclerosis in People Living With Human Immunodeficiency Virus - Takeaways - MDSpire

Distinct Gut Microbiota Signatures Associated With Progression of Atherosclerosis in People Living With Human Immunodeficiency Virus

  • By

  • Mar Masiá

  • José A García

  • Javier García-Abellán

  • Sergio Padilla

  • Marta Fernández-González

  • Vanesa Agulló

  • Maria José Gosalbes

  • Sonia Ruíz-Pérez

  • Paula Mascarell

  • Angela Botella

  • Félix Gutiérrez

  • May 14, 2024

  • 0 min

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  • 1

    A 96-week study linked gut microbiota profiles to atherosclerosis progression in virologically suppressed individuals with HIV.

  • 2

    Carotid intima-media thickness (cIMT) was used to measure atherosclerosis progression, with 43% of participants showing progression.

  • 3

    Distinct microbial profiles were identified, with Agathobacter and Ruminococcus 2 associated with cIMT progression.

  • 4

    Nonprogression of atherosclerosis was consistently linked to the presence of Prevotella 7 in the gut microbiota.

  • 5

    The study highlights the potential role of gut microbiota in cardiovascular disease among people living with HIV.

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