Severity of Respiratory Syncytial Virus and Other Respiratory Viruses Versus Seasonal Influenza Among Hospitalized Patients With Cancer - Takeaways - MDSpire

Severity of Respiratory Syncytial Virus and Other Respiratory Viruses Versus Seasonal Influenza Among Hospitalized Patients With Cancer

  • By

  • Liang En Wee

  • Leicester Shawn Alcantara

  • May Kyawt Aung

  • Shalvi Arora

  • Jean Xiang Ying Sim

  • Dong Dong Ren

  • Zachary Allen Vincent

  • Veeramani Srivathsan

  • Tertius Tansloan Tuy

  • Shin Yeu Ong

  • Wei Chong Tan

  • Iain Beehuat Tan

  • Limin Wijaya

  • Indumathi Venkatachalam

  • Kelvin Bryan Tan

  • Benjamin W Teh

  • Ban Hock Tan

  • November 6, 2025

  • 0 min

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  • 1

    A retrospective cohort study analyzed respiratory viral infections in hospitalized cancer patients from 2018 to 2024 at a Singaporean cancer center.

  • 2

    Among 1823 patients, 24% had influenza, 12.9% had RSV, and 29.4% experienced severe infections requiring oxygen, ICU admission, or death.

  • 3

    RSV and other non-vaccine-preventable RVIs were found to be more severe than seasonal influenza, with higher odds of ICU admission and mortality.

  • 4

    Older age, comorbid conditions, coinfections, and nosocomial transmission were associated with increased severity of RVIs in this population.

  • 5

    The study highlights the need for new vaccines and therapeutics for RVIs, particularly given the significant morbidity and mortality in immunocompromised patients.

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