Patients with Obesity Undergoing Roux-En-Y Gastric Bypass Versus Fundoplication for Refractory GERD: A Systematic Review and Meta-Analysis - Takeaways - MDSpire

Patients with Obesity Undergoing Roux-En-Y Gastric Bypass Versus Fundoplication for Refractory GERD: A Systematic Review and Meta-Analysis

  • By

  • Giovanna Macanhã Scremin

  • Pedro Bicudo Bregion

  • Victor Kenzo Ivano

  • Pandora Eloá Oliveira Fonseca

  • Everton Cazzo

  • March 16, 2026

  • 0 min

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  • 1

    GERD is prevalent in obese patients, complicating treatment due to factors like increased intra-abdominal pressure and hormonal influences.

  • 2

    Fundoplication has higher reflux recurrence rates in obese patients, while Roux-en-Y gastric bypass offers superior reflux control.

  • 3

    RYGB is considered the gold-standard for severe obesity (BMI > 40) due to its effectiveness in diverting gastric acid away from the esophagus.

  • 4

    Novel approaches like the Nissen-sleeve show promise in reflux control, but evidence for moderate obesity remains conflicting.

  • 5

    The systematic review aims to compare RYGB and fundoplication outcomes to guide clinical decisions for obese patients with GERD.

Original Source(s)

Patients with Obesity Undergoing Roux-En-Y Gastric Bypass Versus Fundoplication for Refractory GERD: A Systematic Review and Meta-Analysis

  • by Giovanna Macanhã Scremin, Pedro Bicudo Bregion, Victor Kenzo Ivano, Pandora Eloá Oliveira Fonseca, Everton Cazzo

  • March 16, 2026

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