Predictive value of routine ultrasound indicators in the second trimester for gestational diabetes mellitus: a retrospective cohort study - Takeaways - MDSpire

Predictive value of routine ultrasound indicators in the second trimester for gestational diabetes mellitus: a retrospective cohort study

  • By

  • Chaoran Liu

  • Hao Su

  • Xiaohui Ma

  • Zhihui Liu

  • July 2, 2026

  • 0 min

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  • 1

    This study evaluated the predictive ability of standard second-trimester ultrasound measurements for gestational diabetes mellitus (GDM).

  • 2

    A total of 241 women were analyzed, including 117 with GDM and 124 controls, after excluding certain cases from the initial cohort.

  • 3

    Only amniotic fluid depth showed statistical significance as a predictor for GDM, with a modest AUC of 0.588.

  • 4

    The combined model of pre-pregnancy BMI and six ultrasound Z-scores achieved an AUC of 0.692 but did not reach the clinically useful threshold.

  • 5

    The study concluded that routine fetal ultrasound parameters have limited predictive value for GDM and should not be used for early screening.

Original Source(s)

Predictive value of routine ultrasound indicators in the second trimester for gestational diabetes mellitus: a retrospective cohort study

  • by Chaoran Liu, Hao Su, Xiaohui Ma, Zhihui Liu

  • July 2, 2026

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