Association of DAPT duration with bleeding and ischemic outcomes after percutaneous coronary intervention with drug-coated balloons: a meta-analysis - Takeaways - MDSpire
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Impact of Dual Antiplatelet Therapy Duration on Bleeding and Ischemic Events Following Percutaneous Coronary Intervention with Drug-Coated Balloons: A Meta-Analysis

  • By

  • Giuseppe Panuccio

  • Nicole Carabetta

  • Martina Sportelli

  • Giuseppe Tartaglione

  • Kambis Mashayekhi

  • Emmanouil S. Brilakis

  • David M. Leistner

  • Sabato Sorrentino

  • Youssef Abdelwahed

  • Ulf Landmesser

  • Salvatore De Rosa

  • Daniele Torella

  • May 18, 2026

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  • 1

    Percutaneous coronary intervention with drug-coated balloons offers a stent-free alternative for treating coronary artery disease.

  • 2

    Current guidelines recommend at least 6 months of dual antiplatelet therapy after drug-eluting stent implantation.

  • 3

    The optimal duration of dual antiplatelet therapy after drug-coated balloon angioplasty remains poorly defined.

  • 4

    This meta-analysis aims to evaluate the association between dual antiplatelet therapy duration and clinical outcomes after drug-coated balloon procedures.

  • 5

    Subgroup analyses will explore the impact of different DAPT regimens and lesion settings on bleeding and ischemic events.

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