Facial Hemangiomas May Signal PHACE
Early recognition of segmental facial lesions prompted diagnosis and multidisciplinary care in an infant with multisystem involvement
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By
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Andrea Surnit
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April 14, 2026
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Large segmental facial hemangiomas can indicate PHACE syndrome, which includes various congenital anomalies.
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Diagnosis of PHACE syndrome requires a large facial hemangioma plus at least one major or two minor extracutaneous criteria.
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The reported case involved an infant with multiple abnormalities, including a Dandy-Walker malformation and arterial anomalies.
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Treatment included aspirin, propranolol, and topical timolol, leading to significant clinical improvement.
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Early recognition of PHACE syndrome is crucial to prevent stroke and ensure better long-term outcomes.