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Facial Hemangiomas May Signal PHACE

Early recognition of segmental facial lesions prompted diagnosis and multidisciplinary care in an infant with multisystem involvement

  • By

  • Andrea Surnit

  • April 14, 2026

  • 3 min

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  • 1

    Large segmental facial hemangiomas can indicate PHACE syndrome, which includes various congenital anomalies.

  • 2

    Diagnosis of PHACE syndrome requires a large facial hemangioma plus at least one major or two minor extracutaneous criteria.

  • 3

    The reported case involved an infant with multiple abnormalities, including a Dandy-Walker malformation and arterial anomalies.

  • 4

    Treatment included aspirin, propranolol, and topical timolol, leading to significant clinical improvement.

  • 5

    Early recognition of PHACE syndrome is crucial to prevent stroke and ensure better long-term outcomes.

Original Source(s)

Facial Hemangiomas May Signal PHACE

  • by Andrea Surnit

  • April 14, 2026

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