Brucellosis associated with acute kidney injury and pancytopenia: a case report and review of the literature - Takeaways - MDSpire

Brucellosis associated with acute kidney injury and pancytopenia: a case report and review of the literature

  • By

  • Ya Wang

  • Fangqiu Yu

  • Wei Wang

  • June 12, 2026

  • 0 min

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  • 1

    Brucellosis can affect multiple organ systems, leading to diverse clinical manifestations, including acute kidney injury and haemophagocytic syndrome.

  • 2

    A 51-year-old man presented with fever, acute kidney injury, and progressive pancytopenia, ultimately diagnosed with brucellosis through blood culture.

  • 3

    The patient's renal function and symptoms improved significantly following combined anti-Brucella therapy and etoposide chemotherapy.

  • 4

    Brucellosis is a prevalent zoonotic infection in China, with approximately 40,000 new cases reported annually, primarily affecting those in contact with animals.

  • 5

    Early diagnosis of brucellosis requires detailed history-taking and awareness of its rare complications, as clinical features often lack specificity.

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