Impact of the longitudinal evolution of impaired fasting glucose on cardio-kidney-metabolic multimorbidity - Takeaways - MDSpire

Impact of the longitudinal evolution of impaired fasting glucose on cardio-kidney-metabolic multimorbidity

  • By

  • Guanlin Chen

  • Hong Zheng

  • Yuxian Wang

  • Man Gui

  • Zhen He

  • Zekai Chen

  • Shouling Wu

  • Youren Chen

  • June 16, 2026

  • 0 min

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  • 1

    The study analyzed 43,073 adults to assess the impact of impaired fasting glucose (IFG) on cardio-kidney-metabolic multimorbidity risk.

  • 2

    Over 11 years, 1,795 participants developed multimorbidity, with persistent IFG showing the highest risk compared to sustained normal fasting glucose.

  • 3

    IFG recovery was associated with a lower risk of multimorbidity than progression or persistence, but still higher than those with sustained normal glucose.

  • 4

    The findings emphasize the importance of preventing IFG onset and timely intervention to reduce long-term multisystem health damage.

  • 5

    The study highlights the need for ongoing monitoring of cardio-kidney-metabolic risks even after apparent glycemic recovery.

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