Wound healing outcomes in diabetic kidney disease patients receiving SGLT2 inhibitor therapy: a prospective propensity score-matched cohort study - Takeaways - MDSpire

Wound healing outcomes in diabetic kidney disease patients receiving SGLT2 inhibitor therapy: a prospective propensity score-matched cohort study

  • By

  • Rong-rong Zhang

  • Siyue Huang

  • Xinjie Wang

  • Xiaoqin Li

  • June 3, 2026

  • 0 min

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  • 1

    This study enrolled 247 adults with type 2 diabetes and diabetic kidney disease to evaluate wound healing outcomes with SGLT2 inhibitors.

  • 2

    After matching, 204 patients were analyzed, showing similar median healing times of 33 days for SGLT2 users and 34 days for controls.

  • 3

    No significant differences in wound infection rates were found between SGLT2 inhibitor users and controls during the study.

  • 4

    SGLT2 inhibitor users demonstrated no renal progression events and better eGFR preservation compared to the control group.

  • 5

    The findings suggest that SGLT2 inhibitors do not impair wound healing or increase infection risk in patients with diabetic kidney disease.

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