Distinct nasal and temporal variations in superficial vascular density as early indicators of diabetic retinopathy - Takeaways - MDSpire

Distinct nasal and temporal variations in superficial vascular density as early indicators of diabetic retinopathy

  • By

  • Ziyan Ma

  • Fujuan Yu

  • Huan Li

  • Yang Liu

  • Bolin Deng

  • Yong Zeng

  • January 3, 2026

  • 0 min

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  • 1

    Diabetes Mellitus affects over 537 million adults globally, with China having the highest prevalence, projected to reach 174 million by 2045.

  • 2

    Diabetic retinopathy is the most common complication of diabetes and a leading cause of vision impairment in working-age populations.

  • 3

    Current screening methods for diabetic retinopathy are limited to two-dimensional imaging, which may miss critical three-dimensional vascular changes.

  • 4

    The TowardPi OCT and OCTA system provides a wide-field imaging capability, enhancing the detection of vascular density changes in diabetic retinopathy.

  • 5

    This study compares vascular density across quadrants in healthy individuals, diabetic patients without retinopathy, and those with diabetic retinopathy.

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