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Biomarkers Linked to Future Suicide Risk Improve Predictive Accuracy in Psychiatric Hospitalized Patients

  • By

  • Zheya Cai

  • Enzhao Zhu

  • Jianmeng Dai

  • Xu Zhang

  • Jiayi Wang

  • Xiuake Bahuojia

  • Ruyi Shui

  • Qiuyi Lu

  • Duoduo Bai

  • Shengbei Liu

  • Ruichen Tang

  • Xin Wang

  • Qianyi Yu

  • Han Yang

  • Guoquan Zhou

  • Siqi Liu

  • Zhihao Chen

  • Yuqin Weng

  • Xinyi Tang

  • Huan Wang

  • Huiqing Pan

  • Tongxing Ou

  • Yue Liu

  • Weiwei Xu

  • Kexin Chen

  • Xunuo Lu

  • Wenjing Wang

  • Xuqi Song

  • Zongyuan Wang

  • Feng Wang

  • Dong Wang

  • Kang Ju

  • Liangliang Chen

  • Yichao Yin

  • Chunbo Li

  • Yanping Zhang

  • Pu Ai

  • Tianyu Ji

  • Weizhong Shi

  • Jiaojiao Hou

  • Fazhan Chen

  • Hui Li

  • Zisheng Ai

  • March 27, 2026

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  • 1

    The study analyzed data from 2785 psychiatric inpatients to evaluate biomarkers associated with suicide risk.

  • 2

    Nine biomarkers were identified as linked to elevated suicide risk, while six showed potential protective effects.

  • 3

    Machine learning models incorporating biomarkers and clinical data achieved an area under the curve of 0.808 for predicting suicide risk.

  • 4

    Propensity score matching was used to minimize confounding factors in the analysis of suicide risk.

  • 5

    The findings suggest that integrating biomarkers into suicide risk assessments may enhance objectivity and predictive accuracy.

Original Source(s)

Biomarkers associated with future suicide risk enhance predictive performance in psychiatric inpatients

  • by Zheya Cai, Enzhao Zhu, Jianmeng Dai, Xu Zhang, Jiayi Wang, Xiuake Bahuojia, Ruyi Shui, Qiuyi Lu, Duoduo Bai, Shengbei Liu, Ruichen Tang, Xin Wang, Qianyi Yu, Han Yang, Guoquan Zhou, Siqi Liu, Zhihao Chen, Yuqin Weng, Xinyi Tang, Huan Wang, Huiqing Pan, Tongxing Ou, Yue Liu, Weiwei Xu, Kexin Chen, Xunuo Lu, Wenjing Wang, Xuqi Song, Zongyuan Wang, Feng Wang, Dong Wang, Kang Ju, Liangliang Chen, Yichao Yin, Chunbo Li, Yanping Zhang, Pu Ai, Tianyu Ji, Weizhong Shi, Jiaojiao Hou, Fazhan Chen, Hui Li, Zisheng Ai

  • March 27, 2026

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