Cortisol–CX3CL1 association and altered cytokine–chemokine profiles in emergency medical services personnel - Takeaways - MDSpire

Cortisol–CX3CL1 association and altered cytokine–chemokine profiles in emergency medical services personnel

  • By

  • Elena R. Serrano-Ibáñez

  • María Flores-López

  • Laura Martín-Chaves

  • Tania Corrás-Vázquez

  • Inés Antúnez-Muñoz

  • Javier Samper-Zapata

  • Ada del Mar Carmona-Segovia

  • Raquel Reviriego

  • Manuel Jiménez-Navarro

  • Fernando Rodríguez de Fonseca

  • Antonia Serrano

  • Francisco Javier Pavón-Morón

  • July 10, 2026

  • 0 min

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  • 1

    Emergency medical services (EMS) personnel exhibit higher systolic blood pressure and cortisol levels compared to matched controls.

  • 2

    The EMS group shows increased concentrations of several cytokines and chemokines, including GM-CSF, IL-6, and CX3CL1.

  • 3

    Circulating E-selectin, P-selectin, and sICAM-1 levels are reduced in EMS personnel, indicating altered immune profiles.

  • 4

    Cortisol is selectively associated with CX3CL1, particularly among women, suggesting a unique neuroendocrine–immune interaction.

  • 5

    Women in the EMS group report higher anxiety and stress scores, while men exhibit higher blood pressure levels.

Original Source(s)

Cortisol–CX3CL1 association and altered cytokine–chemokine profiles in emergency medical services personnel

  • by Elena R. Serrano-Ibáñez, María Flores-López, Laura Martín-Chaves, Tania Corrás-Vázquez, Inés Antúnez-Muñoz, Javier Samper-Zapata, Ada del Mar Carmona-Segovia, Raquel Reviriego, Manuel Jiménez-Navarro, Fernando Rodríguez de Fonseca, Antonia Serrano, Francisco Javier Pavón-Morón

  • July 10, 2026

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