Identifying Risk Factors and Developing a Predictive Model for Submucosal Invasion in Early Protruding-Type Esophagogastric Junction Adenocarcinoma: Integrating Conventional Endoscopy with Endoscopic Ultrasonography - Takeaways - MDSpire

Identifying Risk Factors and Developing a Predictive Model for Submucosal Invasion in Early Protruding-Type Esophagogastric Junction Adenocarcinoma: Integrating Conventional Endoscopy with Endoscopic Ultrasonography

  • By

  • Lei Zhang

  • Nana An

  • Zhongfei Jia

  • Xiuli Zheng

  • Wenqian Ma

  • Juntao Lu

  • Limian Er

  • December 3, 2025

  • 0 min

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  • 1

    The incidence of esophagogastric junction adenocarcinoma (EGJAC) is rising in China, complicating preoperative assessments and treatment decisions.

  • 2

    Conventional endoscopy (CE) and endoscopic ultrasonography (EUS) are integrated to evaluate submucosal invasion depth in early protruding-type EGJAC.

  • 3

    The study enrolled 111 patients diagnosed with early protruding-type EGJAC, adhering to strict inclusion and exclusion criteria.

  • 4

    Four distinct macroscopic morphologies of protruding-type early EGJAC were identified, aiding in the assessment of invasion depth.

  • 5

    A risk prediction model was developed to accurately identify submucosal invasion in early protruding-type EGJAC based on clinicopathological parameters.

Original Source(s)

Identifying Risk Factors and Developing a Predictive Model for Submucosal Invasion in Early Protruding-Type Esophagogastric Junction Adenocarcinoma: Integrating Conventional Endoscopy with Endoscopic Ultrasonography

  • by Lei Zhang, Nana An, Zhongfei Jia, Xiuli Zheng, Wenqian Ma, Juntao Lu, Limian Er

  • December 3, 2025

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