Clinical efficacy and safety of porcine fibrin sealant in video-assisted thoracoscopic surgery lobectomy for lung cancer - Takeaways - MDSpire

Clinical efficacy and safety of porcine fibrin sealant in video-assisted thoracoscopic surgery lobectomy for lung cancer

  • By

  • Teng Jia

  • Ming-hui Yue

  • Shu-jing Yin

  • Tian-yu She

  • Xiao-gang Zhao

  • Xiao-jie Gu

  • June 1, 2026

  • 0 min

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  • 1

    Lung cancer is the leading cause of cancer-related mortality, with postoperative complications like pleural effusion and air leaks posing significant challenges.

  • 2

    The study evaluated the safety and efficacy of porcine fibrin sealant (PFS) in video-assisted thoracoscopic lobectomy for lung cancer.

  • 3

    A total of 345 patients were analyzed, with 203 receiving PFS and 142 in the control group, focusing on postoperative drainage and complications.

  • 4

    PFS significantly reduced the duration of chest tube placement and the incidence of pulmonary air leaks compared to the control group.

  • 5

    No significant differences in other complications were observed, and no allergic reactions occurred, indicating good biosafety of PFS.

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