Sanjad–Sakati syndrome: integrated emergency care, long-term management, and expert perspectives—a narrative review - Takeaways - MDSpire

Sanjad–Sakati syndrome: integrated emergency care, long-term management, and expert perspectives—a narrative review

  • By

  • Meshal Atiyah

  • July 14, 2026

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  • 1

    Sanjad–Sakati syndrome (SSS) is a rare autosomal recessive disorder characterized by congenital hypoparathyroidism and persistent hypocalcemia.

  • 2

    SSS presents significant challenges in pediatric emergency care due to multisystem involvement, including endocrine and neurologic complications.

  • 3

    Children with SSS often require urgent calcium correction and airway stabilization due to symptoms like hypocalcemia, seizures, and apnea.

  • 4

    Long-term management of SSS includes lifelong calcium and vitamin D supplementation, regular metabolic monitoring, and psychosocial support.

  • 5

    Early biochemical correction and coordinated multidisciplinary follow-up are critical for improving outcomes in children with SSS.

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