Link Between Triglyceride Glucose–Body Mass Index and Nonunion Rates in Elderly Patients After Limb Fracture Surgery: A Multicenter Retrospective Analysis - Takeaways - MDSpire

Link Between Triglyceride Glucose–Body Mass Index and Nonunion Rates in Elderly Patients After Limb Fracture Surgery: A Multicenter Retrospective Analysis

  • By

  • Xinqun Cheng

  • Zhenbang Yang

  • Chengsi Li

  • Puxin Yang

  • Qingcheng Song

  • Dongwei Wu

  • Tianyu Wang

  • Huilian Sun

  • Yanbin Zhu

  • Wei Chen

  • Yingze Zhang

  • April 24, 2026

  • 0 min

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  • 1

    The study investigates the link between triglyceride glucose–body mass index (TyG–BMI) and nonunion rates in elderly patients post-limb fracture surgery.

  • 2

    A total of 8,499 patients were analyzed, with 141 cases (1.66%) developing nonunion after surgery.

  • 3

    A U-shaped relationship was found between TyG–BMI levels and nonunion risk, with both low and high levels increasing the risk.

  • 4

    TyG–BMI levels below 173.9 and above 213.0 were independently associated with increased nonunion risk.

  • 5

    The findings suggest TyG–BMI could serve as a predictive biomarker for nonunion risk stratification in older fracture patients.

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