Non-specific skin lesions in angioimmunoblastic T-cell lymphoma lead to diagnosis challenge: a case report and literature review - Takeaways - MDSpire

Non-specific skin lesions in angioimmunoblastic T-cell lymphoma lead to diagnosis challenge: a case report and literature review

  • By

  • Zimeng You

  • Qianqian Wang

  • Li Xue

  • Lin Wang

  • Tingting Wang

  • May 14, 2026

  • 0 min

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  • 1

    Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive T-cell lymphoma subtype, affecting the skin in up to 50% of cases.

  • 2

    Cutaneous manifestations of AITL are diverse and non-specific, often leading to misdiagnosis and delayed treatment.

  • 3

    A 63-year-old male presented with skin lesions that progressed to vasculitis-like ulcers, complicating the diagnosis of AITL.

  • 4

    The final diagnosis of AITL was confirmed through lymph node biopsy, highlighting the importance of this procedure.

  • 5

    Clinicians must recognize AITL's cutaneous manifestations to facilitate early and accurate diagnosis, especially before lymphadenopathy.

Original Source(s)

Non-specific skin lesions in angioimmunoblastic T-cell lymphoma lead to diagnosis challenge: a case report and literature review

  • by Zimeng You, Qianqian Wang, Li Xue, Lin Wang, Tingting Wang

  • May 14, 2026

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