Short-term outcomes of a novel anti-reflux biologic flap technique versus double flap technique after laparoscopic proximal gastrectomy: a retrospective cohort study - Takeaways - MDSpire
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Short-Term Outcomes After Laparoscopic Proximal Gastrectomy: Comparing a Novel Anti-Reflux Biologic Flap With the Double-Flap Technique in a Retrospective Cohort Study

  • By

  • Lindi Cai

  • Guanglin Qiu

  • Pengwei Zhao

  • Gan Li

  • Junxiang Zhang

  • Enmeng Li

  • Yongtai Ma

  • Yanjun Sun

  • Mengke Zhu

  • Xinhua Liao

  • Xiangming Che

  • Xuqi Li

  • Lin Fan

  • October 14, 2026

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  • 1

    Proximal gastrectomy is a feasible alternative to total gastrectomy for selected proximal gastric cancers, with comparable survival and better long-term nutritional preservation reported in prior stud

  • 2

    Postoperative reflux is a concern after proximal gastrectomy, and double-flap reconstruction can reduce reflux but is technically challenging and carries a risk of anastomotic stenosis.

  • 3

    The biologic flap technique uses a porcine small intestinal submucosa patch to create a mechanical anti-reflux barrier around the lower esophagus and anastomosis.

  • 4

    This retrospective cohort compared short-term outcomes after laparoscopic proximal gastrectomy with biologic flap or double-flap reconstruction in patients treated from January 2020 through June 2024.

  • 5

    Biologic flap reconstruction uses a tubular stomach and mechanical esophagogastric anastomosis, and was introduced in April 2023 as an alternative for patients with overlapping or more challenging ana

Original Source(s)

Short-term outcomes of a novel anti-reflux biologic flap technique versus double flap technique after laparoscopic proximal gastrectomy: a retrospective cohort study

  • by Lindi Cai, Guanglin Qiu, Pengwei Zhao, Gan Li, Junxiang Zhang, Enmeng Li, Yongtai Ma, Yanjun Sun, Mengke Zhu, Xinhua Liao, Xiangming Che, Xuqi Li, Lin Fan

  • October 14, 2026

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