Sustaining herd immunity against measles: Insights from a serological cohort study in an outbreak-free population - Takeaways - MDSpire

Sustaining herd immunity against measles: Insights from a serological cohort study in an outbreak-free population

  • By

  • Miracle Amadi

  • Simopekka Vänskä

  • Irja Davidkin

  • Heikki Haario

  • Tuija Leino

  • Merit Melin

  • Kari Auranen

  • Mia Kontio

  • May 27, 2026

  • 0 min

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  • 1

    Measles requires over 90% of the population to be immune to achieve herd immunity due to its high basic reproduction number.

  • 2

    Finland eliminated endemic measles by the early 1990s, maintaining vaccination coverage above 95%.

  • 3

    Sustained herd immunity in Finland reflects both protection against infection and interruption of transmission.

  • 4

    The Finnish MMR-vaccinated cohort study monitored antibody levels over 30 years, revealing antibody decline post-vaccination.

  • 5

    An antibody concentration of 120 mIU/ml is considered protective against measles, but assessing full vaccine-induced protection is complex.

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