Application of transvaginal color doppler ultrasound in early diagnosis of threatened abortion and its correlation with serum levels of β - hCG and CA125 - Takeaways - MDSpire

Application of transvaginal color doppler ultrasound in early diagnosis of threatened abortion and its correlation with serum levels of β - hCG and CA125

  • By

  • Li Cao

  • Hongbing Xiang

  • Dongfang Ren

  • Jinsheng Li

  • July 15, 2026

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  • 1

    Transvaginal color Doppler ultrasound (TVCDS) demonstrated 92.86% sensitivity and 100% specificity in diagnosing threatened abortion.

  • 2

    The study included 98 women with threatened abortion and 100 normal pregnant women, comparing serum indicators and ultrasound parameters.

  • 3

    Higher corpus luteum pulsatility index (PI) and resistance index (RI) were found in the observation group, while β-HCG levels were lower.

  • 4

    Multivariate logistic regression identified PI, β-HCG, and CA125 as independent predictors of failed pregnancy preservation.

  • 5

    The combined predictive model yielded an AUC of 0.931, indicating superior efficacy compared to any single indicator.

Original Source(s)

Application of transvaginal color doppler ultrasound in early diagnosis of threatened abortion and its correlation with serum levels of β - hCG and CA125

  • by Li Cao, Hongbing Xiang, Dongfang Ren, Jinsheng Li

  • July 15, 2026

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