Editorial: Molecular pathways and signaling molecules in cancer therapy: advances and innovations - Takeaways - MDSpire

Editorial: Molecular pathways and signaling molecules in cancer therapy: advances and innovations

  • By

  • Abdullah Farhan ul Haque Saeed

  • Sherine Elsawa

  • Chamini Perera

  • July 14, 2026

Share

  • 1

    Cancer is driven by molecular alterations and a dynamic tumor microenvironment, leading to progression and therapeutic resistance.

  • 2

    Molecular pathways like PI3K/AKT/mTOR and RAS/RAF/MEK/ERK are critical targets for precision oncology in cancer treatment.

  • 3

    Advances in multi-omics profiling and AI analysis are revealing pathway-level biomarkers to guide immunotherapy and treatment combinations.

  • 4

    The cGAS-STING pathway plays a dual role in tumor immunity, with potential as a target for small-molecule agonists in cancer therapy.

  • 5

    Lactate is redefined as a signaling molecule influencing tumor plasticity and immune evasion, highlighting new therapeutic strategies.

Original Source(s)

Editorial: Molecular pathways and signaling molecules in cancer therapy: advances and innovations

  • by Abdullah Farhan ul Haque Saeed, Sherine Elsawa, Chamini Perera

  • July 14, 2026

Related Content

Tumor-associated macrophages and lineage plasticity in prostate cancer: from established myeloid programs to emerging spatial hypotheses

A hybrid ViT-L/32–MaxViT-L architecture with adaptive gated fusion for multiclass gastrointestinal disease detection and multi-method post-hoc explainability

Navigating the gut–metabolite–immune axis: enhancing efficacy and mitigating toxicity of immune checkpoint inhibitors