Effect of Remote Ischemic Preconditioning on the Risk of Contrast-Induced Acute Kidney Injury in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention - Takeaways - MDSpire

Effect of Remote Ischemic Preconditioning on the Risk of Contrast-Induced Acute Kidney Injury in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention

  • By

  • Wu, Yanmin

  • Zhang, Xinxin

  • Liu, Peng

  • May 27, 2026

  • 0 min

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  • 1

    Contrast-induced acute kidney injury (CIAKI) is a significant complication following percutaneous coronary intervention (PCI).

  • 2

    Remote ischemic preconditioning (RIPC) may reduce the incidence of CIAKI in coronary heart disease (CHD) patients undergoing PCI.

  • 3

    In a study of 484 patients, RIPC resulted in a lower CIAKI incidence of 6.2% compared to 12.0% in the control group.

  • 4

    Multivariate analysis confirmed RIPC as an independent protective factor against CIAKI with an odds ratio of 0.338.

  • 5

    No significant difference in major adverse cardiac events (MACE) was observed between the RIPC and control groups during follow-up.

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