The effectiveness and safety of oral Chinese patent medicines in treating myocardial infarction complicated with heart failure: a network meta-analysis of 12 interventions - Takeaways - MDSpire

The effectiveness and safety of oral Chinese patent medicines in treating myocardial infarction complicated with heart failure: a network meta-analysis of 12 interventions

  • By

  • Yiying Liu

  • Ruikang Liu

  • Kai Yang

  • Jun Li

  • Guancheng Ye

  • Xuanchun Huang

  • Shiyi Tao

  • Tiantian Xue

  • Yulian Yuan

  • May 21, 2026

  • 0 min

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  • 1

    This study evaluates the efficacy of oral Chinese patent medicines combined with conventional treatment for myocardial infarction with heart failure.

  • 2

    A total of 42 randomized controlled trials were included, assessing 12 oral CPMs and their effects on various clinical outcomes.

  • 3

    Yixinshu capsules showed the best overall clinical effectiveness, while Xintong oral liquid excelled in improving left ventricular ejection fraction.

  • 4

    Guanxin Shutong capsules were most effective in lowering NT-proBNP levels and enhancing exercise tolerance in patients.

  • 5

    The findings suggest that oral CPMs significantly improve cardiac function and quality of life in MI-HF patients, despite limitations in safety reporting.

Original Source(s)

The effectiveness and safety of oral Chinese patent medicines in treating myocardial infarction complicated with heart failure: a network meta-analysis of 12 interventions

  • by Yiying Liu, Ruikang Liu, Kai Yang, Jun Li, Guancheng Ye, Xuanchun Huang, Shiyi Tao, Tiantian Xue, Yulian Yuan

  • May 21, 2026

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