Are prophylactic antibiotics routinely necessary in laparoscopic adnexal surgery? A multicenter cohort study - Takeaways - MDSpire
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Is Routine Antibiotic Prophylaxis Needed for Laparoscopic Adnexal Surgery? A Multicenter Cohort Study

  • By

  • Hiromi Miyata

  • Eiji Kobayashi

  • Miki Yasuda

  • Hungwu Chien

  • Masahiko Takemura

  • Tomoko Tsujie

  • Kyoka Amemiya

  • Akiko Otake

  • Toshiya Yamamoto

  • Eiji Nakatani

  • Michiko Kodama

  • Yutaka Ueda

  • October 19, 2026

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  • 1

    This multicenter retrospective cohort study included patients undergoing laparoscopic adnexal surgery for benign disease at 7 Japanese hospitals from 2020 through 2023.

  • 2

    The primary outcome was surgical site infection within 30 days, compared between patients given preincision cefazolin and those given no prophylactic antibiotics.

  • 3

    Six hospitals routinely administered intravenous cefazolin, whereas one hospital did not routinely use antibiotic prophylaxis.

  • 4

    The study also assessed patient and perioperative factors associated with infection, including body mass index, diabetes, operative time, and blood loss.

  • 5

    The provided context describes the study design and methods but does not report infection rates or results of the risk-factor analyses.

Original Source(s)

Are prophylactic antibiotics routinely necessary in laparoscopic adnexal surgery? A multicenter cohort study

  • by Hiromi Miyata, Eiji Kobayashi, Miki Yasuda, Hungwu Chien, Masahiko Takemura, Tomoko Tsujie, Kyoka Amemiya, Akiko Otake, Toshiya Yamamoto, Eiji Nakatani, Michiko Kodama, Yutaka Ueda

  • October 19, 2026

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