ILEOSTIM trial: a study protocol to evaluate the effectiveness of efferent loop stimulation before ileostomy reversal - Takeaways - MDSpire

ILEOSTIM trial: a study protocol to evaluate the effectiveness of efferent loop stimulation before ileostomy reversal

  • By

  • N. Blanco

  • I. Oliva

  • P. Tejedor

  • E. Pastor

  • A. Alvarellos

  • C. Pastor

  • J. Baixauli

  • J. Arredondo

  • April 27, 2023

  • 0 min

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  • 1

    The ILEOSTIM trial aims to evaluate the effectiveness of efferent loop stimulation before ileostomy reversal to reduce postoperative ileus (POI).

  • 2

    Patients undergoing elective loop ileostomy reversal after low anterior resection for rectal cancer will be included in this multicentre, randomized controlled trial.

  • 3

    Participants will be randomized into intervention and control groups, with the intervention group receiving daily bowel stimulation for two weeks prior to surgery.

  • 4

    Primary outcomes include the development of POIs, while secondary outcomes encompass length of hospital stay, time to oral intake, and various surgical complications.

  • 5

    Mid-term outcomes will assess hospital readmission rates and low anterior resection syndrome (LARS) at one and six months post-surgery.

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