Dual-Energy CT muscle fat fraction as a new imaging biomarker of body composition and survival predictor in critically ill patients

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Sarcopenia, characterized by low muscle strength and mass, is prevalent in critically ill ICU patients and leads to adverse health outcomes.
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Dual-energy CT (DECT) can directly quantify muscle fat content, providing an unbiased assessment of myosteatosis in critically ill patients.
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The study aimed to evaluate changes in muscle status using DECT fat fraction and conventional CT parameters in immobilized ICU patients.
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DECT fat fraction showed good agreement with MRI methods for assessing muscle fat content and may serve as a new imaging biomarker.
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Effective treatment of sarcopenia in ICU patients can reduce hospital stays and complications, highlighting the importance of early detection.

European Radiology

by Jennifer Erley, Kevin Roedl, Ann-Kathrin Ozga, Geraldine de Heer, Niklas Schubert, Julia Breckow, Christoph Burdelski, Enver Tahir, Stefan Kluge, Tobias B. Huber, Jin Yamamura, Gerhard Adam, Isabel Molwitz
May 22, 2024

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