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1
Light chain cardiac amyloidosis (AL-CA) is a severe disease characterized by misfolded monoclonal immunoglobulin light chain deposition in the myocardium.
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2
The patient presented with progressive exertional dyspnea, chest tightness, and recurrent syncope, leading to the diagnosis of AL-CA with bilateral atrial appendage thrombosis.
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3
Cardiac imaging revealed diffuse late gadolinium enhancement consistent with cardiac amyloidosis and thrombi in both atrial appendages.
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4
Despite treatment with anticoagulation and heart failure medications, the patient declined chemotherapy and died from refractory heart failure four months post-diagnosis.
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5
AL-CA is associated with rapid progression and poor prognosis, with median survival often less than six months without timely intervention.
