Acute kidney injury following household pyrethroid aerosol insecticide exposure: a case report and literature review - Takeaways - MDSpire

Acute kidney injury following household pyrethroid aerosol insecticide exposure: a case report and literature review

  • By

  • Yuxin Tang

  • Yuqing Wu

  • Xuhang Xue

  • Sihan Tao

  • Xing Tao

  • Li Li

  • Lianyi Geng

  • Kun Gao

  • Xufang Wang

  • May 28, 2026

  • 0 min

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  • 1

    A case of acute kidney injury (AKI) was linked to exposure to household pyrethroid aerosol insecticides in a previously healthy 55-year-old male.

  • 2

    The patient developed acute tubular necrosis (ATN) and acute interstitial nephritis (AIN) after staying in a poorly ventilated room sprayed with pyrethroids.

  • 3

    Despite initial treatment, the patient's renal function worsened, leading to a kidney biopsy that confirmed nephrotoxicity associated with pyrethroid exposure.

  • 4

    Corticosteroid therapy partially improved the patient's renal function, which stabilized at stage 3 chronic kidney disease (CKD) after three weeks.

  • 5

    This case highlights the potential nephrotoxic effects of pyrethroids, emphasizing the need for clinicians to consider environmental exposures in AKI diagnoses.

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