Research hotspots and trend of the heart-brain axis by MRI: a bibliometric analysis

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The Heart-Brain Axis (HBA) explores the interactions between cardiovascular and central nervous systems, impacting neurological and cardiovascular comorbidities.
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A bibliometric analysis of 6,446 articles from 1984 to 2025 identified four primary research clusters: Technology & Development, Function & Regulation, Risk & Pathology, and Hemodynamics & Perfusion.
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The United States, Germany, and the United Kingdom are the leading contributors to HBA research, with notable institutions including the University of Toronto and Harvard Medical School.
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Keyword analysis revealed high-frequency terms such as 'MRI', 'functional connectivity', 'dementia', and 'hemodynamics', indicating key areas of focus in HBA research.
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The study highlights the growing academic interest in HBA research, emphasizing the need for advanced imaging technologies and AI integration in future studies.

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